Dragon Pharma Enclomiphene 25mcg PCT Tablets

Enclomiphene by Dragon Pharma is a selective estrogen receptor modulator (SERM) formulated at 25 mcg per tablet, supplied in bottles of 100 tabs. Enclomiphene represents the active isomer of clomiphene citrate and is researched for its ability to stimulate natural testosterone production, support hormonal recovery, and assist in male fertility pathways. By targeting the hypothalamic–pituitary–gonadal (HPG) axis, it helps re-establish endogenous hormone balance without introducing exogenous androgens.

What It Is

Enclomiphene Citrate is a purified trans-isomer of clomiphene, designed to selectively antagonize estrogen receptors in the hypothalamus. This reduces negative feedback from circulating estrogens and encourages the body to increase its own testosterone production. Unlike mixed-isomer clomiphene products, Enclomiphene minimizes exposure to the zuclomiphene isomer, which is more often associated with mood swings and visual disturbances. It is widely explored in research relating to secondary hypogonadism, post-androgen recovery, and fertility support in males.

How It Works

Enclomiphene acts as a functional estrogen antagonist in the hypothalamus and pituitary gland. By blocking estrogen's feedback signal, it promotes the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Elevated LH stimulates Leydig cells in the testes to increase endogenous testosterone production, while FSH supports spermatogenesis and testicular function. This upstream mechanism helps restore hormonal output while keeping the testes actively engaged, instead of suppressing them like exogenous androgens do.

Enclomiphene Benefits

• Testosterone Restoration: Encourages the body to produce its own testosterone by increasing LH and FSH.
• Fertility Support: May improve sperm production and quality in research settings.
• Cleaner SERM Profile: Limits exposure to the zuclomiphene isomer, often linked to mood and visual side effects in traditional clomiphene.
• Estrogen Balance: Helps correct estrogen dominance by modulating receptor signaling rather than completely eliminating estrogen.
• Post-Androgen Recovery: Frequently used in studies looking at recovery of the HPG axis after suppressive compound use.

Who It's For

Enclomiphene is intended for adult male where restoration of endogenous testosterone and fertility parameters is a focus. This includes scenarios such as post-androgen recovery models, age-related hormonal decline research, or investigations into secondary hypogonadism. It is not recommended for females, individuals with estrogen-sensitive cancers, or anyone with significant liver disease unless under strict medical supervision. Regular bloodwork and professional oversight are strongly advised in all research applications.

How to Use

Administration: Enclomiphene tablets are taken orally with water, typically once daily at roughly the same time each day to maintain consistent serum levels. It can be taken with or without food, as absorption is not strongly food-dependent.

Protocol Duration: Research protocols often evaluate Enclomiphene over 4–8 weeks to assess changes in LH, FSH, testosterone, and fertility markers. Baseline labs and follow-up testing are essential to document hormonal trends and adjust exposure if needed.

Monitoring: In research, close observation of hormone panels (total and free testosterone, estradiol, LH, FSH), lipid profile, and liver enzymes provides insight into both effectiveness and tolerability. Any visual disturbances, severe mood changes, or unexplained side effects warrant immediate reassessment.

Stacking Suggestions

Enclomiphene is often used as a standalone SERM in recovery designs, but may be combined with supportive lifestyle and supplement strategies:

• Hormone Recovery Stack: Enclomiphene alongside adequate dietary fats, sleep optimization, vitamin D, zinc, and magnesium to maximize natural testosterone output.
• Estrogen Management: In cases of elevated estradiol, low-dose aromatase inhibitors may be explored in research under medical guidance—over-suppression should be avoided.
• Post-Androgen Protocols: Used as the core of a PCT-style design, sometimes followed by a taper or transition to lifestyle-based maintenance once hormonal balance is restored.

Combining Enclomiphene with other SERMs (such as tamoxifen or mixed-isomer clomiphene) is generally unnecessary and may increase side-effect burden without added benefit.

Side Effects

While Enclomiphene is typically better tolerated than traditional clomiphene, side effects can still occur. These may include:

• Neurological: Mild headaches, dizziness, or occasional visual disturbances (blurred vision, halos) in sensitive individuals.
• Mood-Related: Irritability, emotional lability, or transient anxiety as hormone levels shift.
• Gastrointestinal: Nausea, stomach discomfort, or reduced appetite in some subjects.
• Laboratory Changes: Rare alterations in liver enzymes or lipid profile, underscoring the need for routine bloodwork.

Any persistent or severe side effects should trigger dose review or discontinuation in a supervised setting.

Post Cycle Therapy (PCT)

Enclomiphene is frequently used as a central component of PCT-style protocols following cycles that suppress endogenous testosterone production. Its role is to restart and stabilize LH/FSH output and restore normal testicular function. When mild to moderate suppression is present, Enclomiphene alone may be sufficient in many research designs. In cases involving highly suppressive compounds, it may be combined with carefully monitored estrogen management and lifestyle interventions. Once hormonal markers normalize, Enclomiphene is typically tapered and discontinued.