Peptides & HGH

GHRP (Growth Hormone Releasing Peptides) and GHRH (Growth Hormone Releasing Hormone) analogues stimulate GH release through different receptors that work synergistically. GHRPs (Ipamorelin, GHRP-2, GHRP-6, Hexarelin) activate GHS-R1a receptors on pituitary somatotrophs and in the hypothalamus. GHRH analogues (Sermorelin, Tesamorelin, CJC-1295) activate GHRH receptors. Combined, they produce 3-5× synergistic GH pulse amplification versus either alone — the standard protocol is GHRP + GHRH injected simultaneously.

BPC-157 (Body Protection Compound-157) is a 15-amino acid peptide derived from a protein found in gastric juice. It is the most extensively studied cytoprotective repair peptide — documented effects include tendon and ligament healing acceleration, GI tract mucosal protection and repair, anti-inflammatory activity, and nitric oxide pathway modulation. It is used subcutaneously for systemic effects or locally near injury sites for targeted tissue repair. Often combined with TB-500 for comprehensive repair coverage.

Tirzepatide is a dual GLP-1/GIP receptor agonist — it activates both GLP-1 and GIP receptors simultaneously, producing greater weight loss than single GLP-1 agonists like semaglutide. Phase III SURMOUNT trials documented 20-22% body weight reduction with Tirzepatide versus approximately 15% with semaglutide 2.4mg — a clinically meaningful difference attributable to the additional GIP receptor agonism component. Both reduce appetite and slow gastric emptying; Tirzepatide additionally improves insulin sensitivity through the GIP mechanism.

The vast majority of peptides in the Dragon Pharma range require no PCT — they do not suppress the HPG axis or testosterone production. GHRPs, GHRH analogues, BPC-157, TB-500, GHK-Cu, longevity peptides, GLP-1 agonists, Khavinson bioregulators, Thymosin Alpha-1, Kisspeptin and body composition peptides all have no testosterone-suppressive effects. The exception is HMG which is a gonadotropin used specifically for fertility protocols. MK-677 also requires no PCT despite stimulating GH and IGF-1.

Khavinson bioregulators are a class of short peptides (di- through tetrapeptides) developed by Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. Unlike conventional receptor-targeting peptides, they work through an epigenetic mechanism — directly interacting with DNA chromatin to promote demethylation of silenced gene promoters, restoring gene expression patterns suppressed by aging or tissue damage. Each bioregulator is tissue-specific: Testagen targets testicular cells, Ovagen targets liver/GI, Livagen targets immune tissue, and Epitalon targets the pineal gland.

Add bacteriostatic water slowly along the inner wall of the vial — do not inject directly onto the peptide powder as this can cause degradation. The volume of water added determines the concentration: for example, adding 1ml to a 5mg vial gives 5mg/ml (500mcg per 0.1ml). Swirl the vial gently until the powder dissolves — never shake. Store reconstituted peptides refrigerated at 2-8°C and use within 28 days. Never freeze reconstituted peptides.