- Substance: Triodothyronine (L-thyroxine)
- Concentration: 50 mcg/tab
- Form: Oral tablets
- Dosage: 25–100 mcg/day (men and women)
- Manufacturer: Dragon Pharma
- Brand Name: T4, L-thyroxine, Synthroid
SKU: P3888
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T4 - Triodothyronine (L-thyroxine)
T4 by Dragon Pharma contains Triodothyronine (L-thyroxine), a synthetic thyroid hormone delivered in 100 tablets at 50 mcg each. Renowned for its ability to boost metabolism and promote fat loss, T4 is a key tool for bodybuilders in cutting cycles seeking a shredded, energetic physique. With a half-life of approximately 5–7 days, it provides sustained effects with daily dosing.
What It Is
Triodothyronine, commonly known as L-thyroxine or T4, is a synthetic thyroid hormone used medically to treat hypothyroidism. In bodybuilding, it's used off-label to enhance fat loss by increasing metabolic rate and energy expenditure. T4 is a prohormone that converts to the more active T3 (triiodothyronine) in the body, offering a gentler approach to thyroid supplementation compared to direct T3 use, with a lower risk of muscle catabolism when dosed carefully.
How It Works
T4 increases the body's basal metabolic rate by enhancing thyroid hormone activity, promoting fat oxidation and energy expenditure. It upregulates mitochondrial function, boosting thermogenesis and calorie burning. T4 is converted to T3 in peripheral tissues, amplifying its fat-loss effects. However, high doses can increase protein turnover, risking muscle loss without anabolic support. Its half-life of 5–7 days supports stable blood levels, with detection times up to 4–6 weeks in drug tests.
Benefits
- Fat Loss: Accelerates fat burning for a leaner, defined physique.
- Metabolic Boost: Enhances calorie burning and energy expenditure.
- Energy Increase: Improves stamina and workout intensity.
- Muscle Preservation: Gentler than T3, reducing catabolism risk with proper support.
- Non-Hormonal: No direct impact on testosterone or estrogen levels.
Who It's For
T4 is ideal for male and female bodybuilders aged 21–40 in cutting cycles, seeking fat loss and metabolic enhancement while preserving muscle mass. It's suitable for intermediate to advanced users familiar with thyroid hormones. Not for: Individuals under 21, those with hyperthyroidism, cardiovascular issues, or those not under medical supervision. Blood work to monitor thyroid function is essential.
How to Use
Dosage: Typical dosage is 25–100 mcg/day, starting at 25 mcg/day and increasing by 12.5–25 mcg every 4–7 days to assess tolerance. Women typically use 25–75 mcg/day to minimize side effects.
Administration: Take orally with water, preferably in the morning on an empty stomach for optimal absorption. Cycles typically last 4–8 weeks, followed by a 4–8 week break to prevent thyroid suppression. Pair with a high-protein diet (1.5–2 g/lb body weight) and anabolic support (e.g., testosterone) to protect muscle mass.
Results Timeline: Fat loss and energy improvements are noticeable within 1–2 weeks, with significant body composition changes by 4–6 weeks when combined with a calorie-deficit diet and exercise.
Stacking Suggestions
T4 is effective for stacking:
- Cutting Stack: Combine with Clenbuterol (20–80 mcg/day) or Cardarine (10–20 mg/day) for enhanced fat loss and endurance.
- Muscle Preservation: Pair with Testosterone Propionate (100–200 mg/week) to prevent muscle loss.
- Support: Use with Taurine (3–5 g/day) to reduce cramps and support thyroid health.
Side Effects
T4 may cause:
- Thyroid-Related: Temporary thyroid suppression; taper off gradually to restore function.
- Catabolic: Muscle loss at high doses without anabolic support.
- Stimulant-Like: Jitteriness, sweating, insomnia, or rapid heart rate.
- Cardiovascular: Increased blood pressure; monitor regularly.
- Hepatotoxicity: Minimal, but monitor thyroid and liver function.
Regular blood work to monitor thyroid hormones (TSH, T3, T4) is critical.
Post Cycle Therapy (PCT)
T4 does not suppress testosterone, so PCT is not required for hormonal recovery. A tapering protocol (reducing dose by 12.5–25 mcg every 4–7 days) is essential to restore natural thyroid function. If stacked with anabolic steroids, use Clomid (50 mg/day) and Nolvadex (20–40 mg/day) for 4–6 weeks. T4 can be tapered during PCT to maintain fat loss.
Frequently Asked Questions
What is T4?
T4 (L-thyroxine, Triodothyronine) is a synthetic thyroid hormone used for fat loss and metabolic enhancement in bodybuilding and medically for hypothyroidism treatment.
What does T4 do?
T4 boosts metabolism, promotes fat loss, increases energy, and enhances calorie burning, delivering a leaner physique when paired with a calorie-deficit diet.
How long does T4 take to work?
T4 delivers noticeable fat loss and energy improvements within 1–2 weeks, with significant body composition changes by 4–6 weeks with proper diet and training.
Can women use T4?
Yes, women can use T4 at lower doses (25–75 mcg/day) under medical supervision for fat loss, but careful monitoring is needed to avoid thyroid suppression or muscle loss.
How long is T4 detectable?
T4 has a detection time of up to 4–6 weeks in drug tests, depending on dosage, cycle length, and individual metabolism.